Elevated serum aminotransferase activity as an early manifestation of gluten-sensitive enteropathy.

Vajro, P; Fontanella, A; Mayer, M; De Vincenzo, A; Terracciano, L M; D'Armiento, M; Vecchione, R · J Pediatr · 1993

case_series · Level IV

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Abstract

Six children in whom long-standing hypertransaminasemia of unknown cause led to an initial diagnosis of chronic or protracted cryptogenic hepatitis were found to have asymptomatic celiac disease. Administration of a gluten-free diet caused a prompt improvement of both hepatic and intestinal biochemical/histologic abnormalities. Hepatic damage may be another "atypical" form of celiac disease in children.

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