Differential protein binding of ceftizoxime in cord versus maternal serum.
case_control · Level III
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- Record sourced from PubMed, PMID 8456901.
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Abstract
Ceftizoxime concentrations are higher in cord blood and amniotic fluid than in maternal blood. More avid binding to fetal serum proteins is a suggested mechanism. We measured ceftizoxime protein binding in fetal and maternal blood and documented significantly less protein binding to fetal proteins (21.9% vs 57.8%).
Medical subject headings
- Blood Proteins
- Ceftizoxime
- Fetal Blood