Ophthalmic findings in classical galactosaemia--prospective study.

Beigi, B; O'Keefe, M; Bowell, R; Naughten, E; Badawi, N; Lanigan, B · Br J Ophthalmol · 1993

prospective_cohort · Level II

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Abstract

Thirty three children with classical galactosaemia diagnosed through newborn screening are considered. It is concluded that cataract formation has a direct relationship with poor dietary control. Erythrocyte galactose-1-phosphate (Gal-1-P) levels do not correspond to cataract formation unless many times higher than normal. The value of crystalline lens biomicroscopy is confirmed as a useful method for monitoring the dietary and biochemical control in classical galactosaemia.

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