Six generations of a family with multiple limb deficiencies.

Helal, A; Perry, T; Ogden, J A; Greene, T L · J Pediatr Orthop · 1993

case_report · Level V

Where this comes from

Abstract

Ectrodactyly, with or without other limb reduction defects, is a rare congenital anomaly. The pattern of inheritance is usually autosomal dominant, but with variable morphology. We report six generations of a family with this anomaly, with a progressive increase in severity and extent of involvement. Implications of genetic counseling are discussed.

Medical subject headings

Anatomy