ADH and ALDH genotype profiles in Caucasians with alcohol-related problems and controls.
case_control · Level III
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- Record sourced from PubMed, PMID 8461855.
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Abstract
Eighty-two Caucasian patients receiving treatment for alcohol-related problems and eighty four controls were DNA typed for variants in the alcohol dehydrogenase (ADH2 and ADH3) and mitochondrial aldehyde dehydrogenase (ALDH2) gene loci. No association was observed between individual, or combined gene frequencies and the presence of alcohol-related problems.
Medical subject headings
- Alcohol Dehydrogenase
- Alcoholism
- Aldehyde Dehydrogenase
- Genotype
- Isoenzymes