Limited therapeutic effect of addition of buspirone in fluvoxamine-refractory obsessive-compulsive disorder.
rct · Level II
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Abstract
The authors found that buspirone added to the treatment of 33 patients with obsessive-compulsive disorder who were refractory to the serotonin reuptake inhibitor fluvoxamine was no better than placebo in reducing obsessive-compulsive, depressive, or anxiety symptoms. This finding suggests that addition of buspirone to ongoing fluvoxamine therapy is not an effective treatment strategy for most patients with obsessive-compulsive disorder.
Medical subject headings
- Buspirone
- Fluvoxamine
- Obsessive-Compulsive Disorder