Biochemical markers of nutrition in osteoporosis.

Rico, H; Relea, P; Revilla, M; Hernandez, E R; Arribas, I; Villa, L F · Calcif Tissue Int · 1993

case_control · Level III

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Abstract

Thirty-six women with vertebral osteoporosis showed significantly decreased levels of biochemical markers of nutrition, transferrin (P < 0.001), prealbumin (P < 0.001), retinol binding-protein (P < 0.001), and fibronectin (P < 0.001), compared with 40 healthy women of similar age. Multiple regression analysis showed a significant (R2 = 0.509; P = 0.0068) correlation between bone mineral content and biochemical markers of nutrition in the osteoporotic patients but not in the control group. These data suggest that postmenopausal osteoporosis may be associated with a nutritional deficiency.

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