Endocarditis caused by Brucella melitensis.
case_report · Level V
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- Record sourced from PubMed, PMID 8479384.
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Abstract
OBJECTIVE: To describe the management of an uncommon but serious infection in Australia. CLINICAL FEATURES: A 25-year-old woman developed endocarditis after residence in Turkey and consumption of goat dairy products. Brucella melitensis was isolated from blood cultures. INTERVENTION AND OUTCOME: The valve remained infected after prolonged intravenous administration of trimethoprim-sulfamethoxazole, gentamicin and rifampicin. Uncontrolled sepsis and worsening haemodynamic function necessitated valve replacement. To date the patient remains well while taking trimethoprim-sulfamethoxazole and rifampicin. CONCLUSION: Endocarditis due to Brucella spp. is uncommon in Australia. This infection is difficult to cure with antimicrobial therapy alone and early surgical intervention is advisable.