Retinoid hepatitis.
case_report · Level V
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- Record sourced from PubMed, PMID 8491880.
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Abstract
A 65-year-old woman treated with etretinate for pityriasis rubra pilaris developed chronic active hepatitis. The elevated transaminases were noted 2 months after initiation of therapy and peaked 2 months after discontinuation of etretinate. The spectrum of liver toxicity induced by etretinate is reviewed. We suggest that reported cases of retinoid-induced liver disease can be divided into four distinct categories: nonspecific reactive hepatitis, acute hepatitis, chronic active hepatitis, and severe fibrosis or cirrhosis.
Medical subject headings
- Chemical and Drug Induced Liver Injury
- Etretinate