Gold therapy lowers serum interleukin 6 levels in rheumatoid arthritis.
prospective_cohort · Level II
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Abstract
To determine the clinical utility and the effect of sodium aurothiomalate (GSTM) on serum interleukin 6 (IL-6) levels in patients with rheumatoid arthritis (RA). Open prospective study of 50 patients with RA treated with GSTM. Serum IL-6 measured by bioassay. IL-6 showed correlations with Ritchie articular index, duration of morning stiffness and C-reactive protein. GSTM significantly reduced IL-6 levels. IL-6 is a potentially useful additional indicator of disease activity in RA and is modulated by GSTM.
Medical subject headings
- Arthritis, Rheumatoid
- Gold Sodium Thiomalate
- Interleukin-6