Serial measurements of neuropeptide Y in plasma for monitoring neuroblastoma in children.
case_series · Level IV
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Abstract
Neuropeptide Y (NPY) was studied as a marker for neuroblastoma in 12 children. All but one patient with neuroblastoma had elevated plasma NPY concentrations at diagnosis. During treatment NPY values returned to normal in 9 of 12 children. All three children without normalization of plasma NPY values died; two of them had a relapse and the third died of toxic effects. Plasma NPY appears to be a sensitive marker of neuroblastoma.
Medical subject headings
- Biomarkers, Tumor
- Neuroblastoma
- Neuropeptide Y