Mazindol treatment for cocaine dependence.
rct · Level II
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- Record sourced from PubMed, PMID 8556974.
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Abstract
This double-blind placebo-controlled treatment study tested the efficacy of mazindol in currently cocaine-dependent out-patients. Forty-three patients were randomized to mazindol (2 mg QD) vs. placebo treatment for 6 weeks. All patients received weekly group counseling. Patients improved with respect to objective (urine toxicology) and subjective (self-report of times used, dollars spent, craving, etc.) measures. There was no response difference between patients treated with mazindol and those who received placebo.
Medical subject headings
- Central Nervous System Stimulants
- Cocaine
- Mazindol
- Substance-Related Disorders