Melatonin replacement corrects sleep disturbances in a child with pineal tumor.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 8559393.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A child with a germ cell tumor involving the pineal region had marked suppression of melatonin secretion associated with severe insomnia. Exogenous melatonin (3 mg in the evening) for 2 weeks restored sleep continuity, as demonstrated by objective monitoring of rest-activity cycles. This case report provides direct evidence of the essential role of melatonin in normal sleep.
Medical subject headings
- Brain Neoplasms
- Melatonin
- Pineal Gland
- Sleep
- Sleep Initiation and Maintenance Disorders