Lipid peroxidation in cord blood at birth.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 8572035.
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Abstract
The purpose of this study was to determine oxygen free radical activity in the neonate at birth and relate it to umbilical cord blood acid-base status. A series of 110 singleton deliveries had determination of two lipoperoxides in umbilical cord blood: malondialdehyde and organic hydroperoxide. Umbilical pH, PO2, PCO2, bicarbonate, and base excess were also measured. There was a significant association between lipoperoxides and cord blood pH and base excess. A significant difference existed in the levels of umbilical artery lipoperoxides between nonacidemic and acidemic fetus, as defined by an umbilical arterial pH < 7.20. There is a positive association between lipoperoxide production and acid-base balance at delivery.
Medical subject headings
- Fetal Blood
- Lipid Peroxidation