The clinical significance of an autoimmune response against glutamic acid decarboxylase.
review · Level V
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Abstract
Glutamic acid decarboxylase is attracting much interest because of its putative involvement in two clinical disorders: stiffman syndrome and insulin-dependent diabetes. Here we discuss the clinical significance of an autoimmune response against GAD and consider how such information may help identify the disease mechanisms of these disorders.
Medical subject headings
- Autoimmunity
- Diabetes Mellitus, Type 1
- Glutamate Decarboxylase
- Stiff-Person Syndrome