Facioscapulohumeral muscular dystrophy with chromosome 9p deletion.

Ueyama, H; Kumamoto, T; Mita, S; Kimura, E; Nakagawa, M; Uchino, M; Ando, M · Neurology · 1996

case_report · Level V

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Abstract

We report a 31-year-old man with facioscapulohumeral muscular dystrophy who had congenital anomalies and mental retardation. Southern blot analysis, using the probe p13E-11, displayed an abnormal EcoRI DNA fragment that reflect DNA rearrangements in facioscapulohumeral muscular dystrophy. In addition, high-resolution cytogenetic study revealed an interstitial deletion of the short arm chromosome 9: 46,XY,del(9)(p.22.1p24.1).

Medical subject headings

Anatomy