Surgical outcome in acquired immunodeficiency syndrome patients with non-Hodgkin's lymphoma of the gastrointestinal tract.

Abstract

Incidence of non-Hodgkin's lymphoma (NHL) has shown a dramatic increase, concurrent with the epidemic of acquired immunodeficiency syndrome (AIDS). In terms of surgical intervention, management of the patient with AIDS-NHL remains unclear. Purpose of this paper was to determine the role and outcome of surgical intervention in patients with AIDS-NHL of the gastrointestinal (GI) tract. Data were obtained by retrospective chart review. From 1980 to 1993, charts of 22 patients with diagnosis of AIDS-NHL of the GI tract who underwent either biopsy or surgical procedure were reviewed. All patients were male, with a mean age of 35.7 years. Sixty-seven biopsies were performed in the 22 patients identified. No morbidity or mortality was associated with any of the biopsy procedures. Major intra-abdominal operations were performed in eight patients, including seven who underwent primary resections of lymphomas. Mean survival for the group as a whole was 18 months, although that for the seven patients undergoing resection was 20.4 months. Diagnosis of AIDS-NHL of the GI tract should not discourage performance of otherwise appropriate surgical procedures.