Persistence of fetal hemoglobin production after successful transplantation of cord blood stem cells in a patient with sickle cell anemia.
case_report · Level V
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- Record sourced from PubMed, PMID 8636820.
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Abstract
A girl with sickle cell anemia was treated with cord blood transplantation combined with hematopoietic growth factor. Cord blood cells were collected from a sister with an identical human leukocyte antigen complex who was a carrier of the sickle cell trait (hemoglobin AS). The patient had complete engraftment and no graft-versus-host disease. The persistence of a high level of fetal hemoglobin 6 months after engraftment was noted.
Medical subject headings
- Anemia, Sickle Cell
- Fetal Blood
- Fetal Hemoglobin