Macrophage activation syndrome in systemic juvenile rheumatoid arthritis successfully treated with cyclosporine.
case_report · Level V
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Abstract
A macrophage activation syndrome, possibly related to methotrexate toxicity, developed in a boy with systemic juvenile rheumatoid arthritis. Corticosteroid administration was ineffective, whereas a prompt response to cyclosporine was observed. Two months later, Pneumocystis carinii pneumonia developed.
Medical subject headings
- Antirheumatic Agents
- Arthritis, Juvenile
- Cyclosporine
- Macrophage Activation
- Methotrexate