High-dose oral dexamethasone therapy for chronic childhood idiopathic thrombocytopenic purpura.

Adams, D M; Kinney, T R; O'Branski-Rupp, E; Ware, R E · J Pediatr · 1996

case_series · Level IV

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Abstract

Because high-dose oral dexamethasone therapy has been reported to be effective for adults with idiopathic thrombocytopenic purpura, we assessed the short-term efficacy and toxicity of dexamethasone in seven children with chronic or refractory idiopathic thrombocytopenic purpura. Dexamethasone therapy was effective and well tolerated; further long-term studies are warranted.

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