Lung transplantation in chronic airflow limitation.

Lynch, J P; Trulock, E P · Med Clin North Am · 1996

review · Level V

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Abstract

Lung transplantation is an option for appropriately selected patients with end-stage chronic airflow limitation. The functional results have been excellent after single or bilateral lung transplantation, and the medium-term survival results have been good. Obliterative bronchiolitis, however, thought to be a manifestation of chronic rejection, occurs in approximately 40% of recipients, and it is the major cause of late morbidity and mortality in lung transplant recipients.

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