Laboratory evaluation of pediatric bone and soft-tissue tumors.

Craver, R D · Orthop Clin North Am · 1996

review · Level V

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Abstract

This article discusses how specimens are approached and handled by the laboratory. Basic histology is reviewed. Contributions by electron microscopy and immunoperoxidase staining are briefly discussed. Current uses of DNA indices, cytogenetic analysis, and new molecular diagnostic advances are highlighted. Proper communication between the pathologist and the orthopedist is the cornerstone for optimal use of laboratory resources.

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