The evolution of chemotherapeutic agents for the treatment of pediatric musculoskeletal malignancies.
review · Level V
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Abstract
The incorporation of antineoplastic agents in the treatment of pediatric musculoskeletal malignancies and their impact in the management and outcome of patients with these types of malignancies are briefly reviewed. The role of chemotherapy in the management of these tumors with special emphasis on osteosarcoma, Ewing's sarcoma family of tumors, and rhabdomyosarcoma and undifferentiated sarcomas is discussed. Also included are complications and side effects of the antineoplastic agents.
Medical subject headings
- Bone Neoplasms
- Muscle Neoplasms