The relationship between anaesthetic uptake and cardiac output.
case_series · Level IV
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- Record sourced from PubMed, PMID 8669560.
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Abstract
The hypothesis that anaesthetic uptake during maintenance of anaesthesia is related to cardiac output was tested on 21 patients undergoing cardiac surgery. Using a computer-controlled closed breathing system, enflurane was administered to maintain an end-expired concentration of 1%. Cardiac output was measured by thermodilution using a pulmonary artery catheter. A clear qualitative but not quantitative relationship was demonstrated. Changes in anaesthetic requirements at a constant end-expired concentration are a better guide to changes in cardiac output than changes in end-expired carbon dioxide with constant ventilation in patients undergoing cardiac surgery.
Medical subject headings
- Anesthetics, Inhalation
- Cardiac Output
- Enflurane