CD40 ligand deficiency presenting as unresponsive neutropenia.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 8669967.
- Also identified by PMC identifier 1511550.
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Abstract
A male child presented with recurrent respiratory infections, otitis media, and oral ulceration and was found to be neutropenic. Investigations showed hypogammaglobulinaemia with normal serum IgM and a novel deletion in the gene for CD40 ligand on his X chromosome. Intravenous gammaglobulin did not lead to resolution of his neutropenia; G-CSF was also necessary.
Medical subject headings
- Agammaglobulinemia
- CD40 Antigens
- Neutropenia