Budd-Chiari syndrome attributed to protein C deficiency.

Sugano, S; Suzuki, T; Makino, H; Yanagimoto, S; Nishio, M; Onmura, H; Iinuma, M; Matuda, T et al. · Am J Gastroenterol · 1996

case_report · Level V

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Abstract

The protein C anticoagulant pathway is an important downregulating mechanism of the blood coagulation cascade. We report a 47-yr-old male with Budd-Chiari syndrome and occlusion of the inferior vena cava. His plasma protein C antigen level was decreased to 42%, and its activity was 34%. Other coagulable factors were normal. Protein C deficiency should be considered a possible etiological factor of the Budd-Chiari syndrome.

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