Metoclopramide and prochlorperazine do not decrease propofol hypnotic requirements.
rct · Level II
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Abstract
One hundred patients scheduled for minor surgery were given either saline, metoclopramide 0.1 mg.kg-1 or 0.2 mg.kg-1, or prochlorperazine 0.1 mg.kg-1 or 0.2 mg.kg-1 before induction of anaesthesia with a fixed rate infusion of propofol. Neither metoclopramide nor prochlorperazine reduced the induction dose of propofol. The possibility that these agents increased the induction dose could not be excluded.
Medical subject headings
- Anesthetics, Intravenous
- Antiemetics
- Metoclopramide
- Prochlorperazine
- Propofol