Taste receptor-like cells in the rat gut identified by expression of alpha-gustducin.
basic_science · Level V
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- Record sourced from PubMed, PMID 8692869.
- Also identified by PMC identifier 39077.
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Abstract
The alpha-subunit of the trimeric G-protein complex specific for taste receptor cells of the tongue, alpha-gustducin, is described here to be also expressed in the stomach and intestine. The alpha-gustducin-containing cells were identified as brush cells that are scattered throughout the surface epithelium of the gut and share structural features of taste receptor cells of the tongue. These findings provide clues to the long-sought molecular and cellular basis for chemoreception in the gut.
Medical subject headings
- Gastric Mucosa
- Intestinal Mucosa
- Sensory Receptor Cells
- Taste
- Transducin