Use of liposome-associated bupivacaine in a cancer pain syndrome.
case_report · Level V
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Abstract
Bupivacaine 0.25% encapsulated by multilamellar liposomes was administered epidurally to a patient suffering pain associated with lung cancer and the effect compared with a plain bupivacaine solution of the same concentration. Complete analgesia was produced for 4 h with the plain solution and 11 h with the liposomal formulation. No motor blockade or haemodynamic instability was observed with the liposome-associated bupivacaine.
Medical subject headings
- Analgesia, Epidural
- Anesthetics, Local
- Bupivacaine
- Lung Neoplasms
- Intractable Pain