Cerebral haemodynamics during thoracic- and thoracoabdominal aortic aneurysm repair.
prospective_cohort · Level II
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Abstract
To investigate cerebral haemodynamics during operations for thoracic and thoracoabdominal aortic aneurysms. Prospective clinical study. 10 patients operated on consecutively with resection for thoracic (5) or thoracoabdominal aortic (5) aneurysms. Blood flow velocity of the middle cerebral artery was measured through a temporal approach using a TC Doppler with a 2 MHz probe. Recordings were made during induction of anaesthesia and performed continuously before, during and after cross-clamping of the aorta. Following 10 min. of aortic cross-clamping blood flow velocity of the middle cerebral artery increased from 44 to 55 cm/s (p < 0.01). A further increase to 69 cm/s (p < 0.01) was observed 5 min after declamping. The pulsatility index averaged 0.74 increasing to 1.21 (p < 0.05) at clamping and 0.87 (p < 0.05) after declamping. There was an increased blood flow velocity of the middle cerebral artery during cross-clamping of the descending thoracic aorta in patients operated on for thoracic and thoracoabdominal aortic aneurysms. This increase in cerebral blood flow and blood volume could explain the acute increase in cerebrospinal fluid pressure observed during cross-clamping of the thoracic aorta.
Medical subject headings
- Aortic Aneurysm, Abdominal
- Aortic Aneurysm, Thoracic
- Cerebral Arteries