Treatment of scleromyxedema with 2-chlorodeoxyadenosine.
case_report · Level V
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Abstract
Scleromyxedema is an unusual skin disease that is characterized by a proliferation of fibroblasts and an accumulation of mucin. Despite experience with multiple forms of therapy, no single agent has proved uniformly beneficial in this condition. We describe a patient with scleromyxedema who was treated successfully with 2-chlorodeoxyadenosine (2-CdA), a purine analog used mainly in the treatment of lymphoproliferative disorders.
Medical subject headings
- Cladribine
- Immunosuppressive Agents
- Myxedema
- Scleroderma, Systemic