Cutaneous manifestations of congenital afibrinogenaemia.

Rupec, R A; Kind, P; Ruzicka, T · Br J Dermatol · 1996

case_report · Level V

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Abstract

Skin problems from coagulation disorders have rarely been described in the dermatological literature. Here we report a patient with a complete congenital absence of fibrinogen which led to leg ulceration, necrosis of the toes and a life-threatening haemorrhage following skin biopsy. This patient shows that leg ulcers may have a complex aetiology and can reflect serious underlying disease.

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