Lessons from the late diagnosis of isovaleric acidemia in a five-year-old boy.

Mehta, K C; Zsolway, K; Osterhoudt, K C; Krantz, I; Henretig, F M; Kaplan, P · J Pediatr · 1996

case_report · Level V

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Abstract

Chronic, intermittent isovaleric acidemia was undiagnosed in a boy with an increased anion gap metabolic acidosis until the boy was 5 years of age. This case emphasizes the importance of maintaining a high index of suspicion for inborn errors of metabolism in patients with metabolic acidosis, even in late childhood.

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