Isolated late asthmatic reaction after exposure to a high-molecular-weight occupational agent, subtilisin.
case_report · Level V
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- Record sourced from PubMed, PMID 8797431.
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Abstract
High-molecular-weight agents generally induce immediate asthmatic reactions. We report the case of a subject who experienced a reaction that started after the first hour following exposure to subtilisin, a high-molecular-weight occupational agent. Any occurrence of immediate reaction was ruled out by measuring both FEV1 and lung volumes every 10 min in the first hour. This reaction was IgE-mediated as shown by immediate skin reactivity and increased specific IgE levels.
Medical subject headings
- Asthma
- Occupational Diseases
- Occupational Exposure
- Subtilisins