Effect of six months of growth hormone therapy, followed by treatment withdrawal in short children with normal quantitative indexes of growth hormone secretion.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 8804340.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Eight short patients with normal 24-hour integrated concentration of growth hormone by continuous withdrawal (IC-GH) received 6 months of GH therapy, followed by 6 months off. GH therapy increased growth rate (+2.9 cm/yr), repeated IC-GH (sixfold), and IGF-1 concentration (twofold). Posttreatment growth reverted to the pretreatment rate. Thus increased growth rate and IGF-1 concentration is associated with supraphysiologic IC-GH after injection.
Medical subject headings
- Growth Disorders
- Growth Hormone