Clonidine in the management of asymmetrical gustatory facial sweating: an N-of-1 trial.
rct · Level II
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Abstract
To determine the efficacy of clonidine in the management of gustatory facial sweating (GFS) ipsilateral to an upper thoracic sympathectomy. Placebo-controlled N-of-1 trial. Tertiary care referral center. Clonidine patch that delivers 0.2mg/d. Daily episodes of GFS are recorded. The severity of GFS is graded as mild, moderate, or severe, and a daily GFS score is calculated. Clonidine was shown to significantly decrease (p < .05) the incidence and frequency of gustatory facial sweating.
Medical subject headings
- Adrenergic alpha-Agonists
- Clonidine
- Ganglia, Sympathetic
- Ganglionectomy
- Sweating, Gustatory