Suppression of systemic lupus erythematosus by the human immunodeficiency virus.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 8823711.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
We describe a patient with refractory systemic lupus erythematosus (SLE) who demonstrated complete resolution of all SLE symptoms. He was subsequently found to be infected with the human immunodeficiency virus (HIV-1) and had marked depletion of peripheral CD4 positive T lymphocytes. In addition, while his SLE remained completely inactive, the course of HIV was rapidly progressive, suggesting that retroviral replication may have been enhanced by the underlying state of T cell transactivation characteristic of SLE.
Medical subject headings
- HIV Infections
- HIV-1
- Immune Tolerance
- Lupus Erythematosus, Systemic