Inorganic fluoride concentration after long-term sedation with isoflurane.

Osborne, M A; Eddleston, J M; McNicoll, W · Intensive Care Med · 1996

case_report · Level V

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Abstract

We report on five patients in whom long-term sedation with isoflurane for up to 7 days was used successfully. Serum inorganic fluoride concentrations were measured daily. The concentrations ranged from 12 mmol l-1 to 29 mmol l-1. These were well below the described renal toxic level of 50 mmol l-1. There was no deterioration in renal function attributable to the use of isoflurane.

Medical subject headings