Aneurysm formation in modified human umbilical vein grafts.

Abstract

Aneurysm formation in Human Umbilical Vein Grafts has been reported to be as high as 65% after 5 years. One of the causes might be the structure of the Biograft-wall and in 1985 a new method of processing the graft was begun. In Groningen this new improved Biograft has been used since late 1986. Duplex scanning was used to examine the frequency of aneurysm formation in the new improved Biograft. Sixty-nine patent Biografts have been examined in a period up to 6 years after implantation. Aneurysms were found in only 17% of grafts although the frequency increased with time. Dilatation was common but may be due to a more elastic graft. These findings justify the continued use of the new Biograft as a substitute for arterial femoropopliteal reconstructions.