Phonologic processing deficits in Alzheimer's disease.

Biassou, N; Grossman, M; Onishi, K; Mickanin, J; Hughes, E; Robinson, K M; D'Esposito, M · Neurology · 1995

cross_sectional · Level IV

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Abstract

We investigated phonologic production in patients with mild to moderate Alzheimer's disease (AD) on a repetition task. AD patients produced significantly more speech errors than age-matched controls. AD patients' errors, unlike those of controls, resulted in the transformation of real words into pseudowords, occurred disproportionately in word-initial positions, and were not influenced by the phonologic environment. This pattern of errors suggests a lexical phonologic retrieval deficit in AD.

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