Promotion of calcification on carboxymethylchitin discs.
basic_science · Level V
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- Record sourced from PubMed, PMID 8853124.
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Abstract
A series of water-insoluble carboxymethylchitin (CM-chitin) discs of varying degrees of substitution (d.s.) has been investigated for their interaction with calcium phosphate. Discs of d.s. 0.03, 0.11, 0.14 and 0.23 were prepared by casting from solutions of CM-chitin in 90% formic acid. Calcium uptake and calcium phosphate nucleation were found to increase with the degree of substitution of the CM-chitin discs. The results suggest that water-insoluble CM-chitin may be useful as a platform for in vivo calcification.
Medical subject headings
- Calcium
- Calcium Phosphates
- Chitin