Olanzapine in the treatment of dopaminomimetic psychosis in patients with Parkinson's disease.

Wolters, E C; Jansen, E N; Tuynman-Qua, H G; Bergmans, P L · Neurology · 1996

case_series · Level IV

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Abstract

We studied the effect of olanzapine (1 to 15 mg/d) in 15 nondemented parkinsonian patients with drug-induced psychosis. Psychotic symptoms decreased significantly during treatment, and there was no worsening of extrapyramidal symptoms. These results suggest that olanzapine is a well-tolerated and effective treatment for drug-induced psychosis in nondemented patients with Parkinson's disease.

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