Effect of water diuresis and water restriction on expression of HSPs-27, -60 and -70 in rat kidney.
basic_science · Level V
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Abstract
Expression of HSP-27, HSP-60 and HSP-70 was estimated in the cortex, outer medulla and inner medulla (papilla) of rats undergoing water diuresis or water restriction for two days. The mRNAs for HSP-27 and HSP-60 in renal papilla were two- to threefold greater in rats during water restriction than in those excreting a dilute urine, but levels of mRNA for HSP-70 were not reduced by water diuresis and Western analysis for HSP-70 protein showed no difference between water-loaded and water-restricted animals.
Medical subject headings
- Chaperonin 60
- Diuresis
- HSP70 Heat-Shock Proteins
- Heat-Shock Proteins
- Kidney
- Water Deprivation