Seven year prognosis in depression. Mortality and readmission risk in the Nottingham ECT cohort.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 8894191.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The longer term prognosis of depressed patients treated with ECT is relatively unknown. We describe seven-year mortality and readmission risks for the Nottingham ECT series. Cases were defined and subtyped using the Present State Examination (PSE). Follow-up was naturalistic. Death and readmission were ascertained using the Nottingham case register. The risk of death was doubled (SMR = 1.99, 95% CI = 1.34-2.84, P < 0.001). The seven-year cumulative probability of remaining without readmission was 0.27 (95% CI 0.19-0.35), being 0.79 (0.71-0.87) at 16 weeks (relapse) and 0.34 (0.24-0.44) thereafter (recurrence readmissions). Multiple regression analysis showed that delusions predicted relapse, while endogenous subtype, absence of psychomotor retardation, and previous history predicted recurrence readmissions. Index ECT treatment predicted high longer-term mortality and readmission risks. PSE/CATEGO-based subtyping identified patients most vulnerable to relapse and recurrence.
Medical subject headings
- Depressive Disorder
- Electroconvulsive Therapy
- Patient Readmission