The combinatorial chemistry of nature.
review · Level V
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- Record sourced from PubMed, PMID 8895593.
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Abstract
Powerful new technologies such as high-throughput screening and combinatorial chemistry are revolutionizing drug discovery. But natural products still offer unmatched structural variety, especially as new environmental niches are explored, and their usefulness can be further extended by engineering the proteins that produce them and by using them to probe biological pathways.
Medical subject headings
- Chemistry, Pharmaceutical
- Pharmaceutical Preparations