Recent developments in cerebral monitoring--near-infrared light spectroscopy. An overview.
review · Level V
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Abstract
A recent development has been the resurgence of interest in the concept of near-infrared light spectroscopy as a method of monitoring cerebral perfusion. Although this technique has been in use for 40 years, the principle has been primarily employed in peripheral pulse oximetry. Infrared light of wavelengths 600-1300 nanometres (nm) penetrate human tissue to a depth of several centimetres. Within the human brain this light is attenuated by the chromophores oxyhaemoglobin, deoxyhaemoglobin and also oxidised cytochrome a3. Positioning a near-infrared light source and a photodetector in a side by side configuration detects light attenuated and reflected in a parabolic path through the scalp, skull and brain tissue.
Medical subject headings
- Cerebrovascular Circulation
- Monitoring, Physiologic
- Spectroscopy, Near-Infrared