Scleroderma-polymyositis overlap syndrome associated with anti-Ku antibody and rimmed vacuole formation.
case_report · Level V
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- Record sourced from PubMed, PMID 8923381.
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Abstract
Scleroderma-polymyositis overlap syndrome is strongly associated with certain autoantibodies, such as anti-PM-Scl antibody and anti-Ku antibody. We describe a case of scleroderma-polymyositis overlap syndrome associated with anti-Ku antibody, which revealed rimmed vacuole formation in addition to intranuclear and intracytoplasmic filamentous inclusions in muscle biopsy specimens.
Medical subject headings
- Antigens, Nuclear
- Autoantibodies
- DNA Helicases
- DNA-Binding Proteins
- Muscle, Skeletal
- Nuclear Proteins
- Polymyositis
- Scleroderma, Systemic
- Vacuoles