Diphenhydramine overdose during pregnancy: lessons from the past.

Brost, B C; Scardo, J A; Newman, R B · Am J Obstet Gynecol · 1996

case_report · Level V

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Abstract

A primigravid woman was seen for the first time in a disoriented and combative state, with regular, painful uterine contractions. Evaluation revealed a negative illicit drug screen, no evidence of preeclampsia, and a nonfocal neurologic examination. Further workup revealed urinary diphenhydramine levels suggesting drug overdose. This case serves as a reminder of the oxytocin-like effects of diphenhydramine.

Medical subject headings