Acromegaly presenting with diabetic ketoacidosis.

Katz, J R; Edwards, R; Khan, M; Conway, G S · Postgrad Med J · 1996

case_report · Level V

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Abstract

Diabetes in acromegaly is usually non-insulin dependent and is secondary to insulin resistance caused by growth hormone excess. Diabetic ketoacidosis is a result of relative insulin deficiency and is a rare feature of acromegaly. We describe a case of acromegaly presenting with diabetic ketoacidosis. We demonstrate that growth hormone excess can cause diabetic ketoacidosis in the presence of relative, but not absolute insulin deficiency.

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