Treatment of hyperemesis gravidarum with the 5-HT3 antagonist ondansetron (Zofran).
case_report · Level V
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- Record sourced from PubMed, PMID 8944215.
- Also identified by PMC identifier 2398636.
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Abstract
Ondansetron is a 5-hydroxytryptamine receptor antagonist which is known to be a highly effective anti-emetic drug for chemotherapy-associated nausea and vomiting and for postoperative nausea. We report here a case where ondansetron was used in severe hyperemesis gravidarum to avoid parenteral nutrition. The drug was used intermittently in every trimester with no apparent adverse effects on mother or infant.
Medical subject headings
- Antiemetics
- Hyperemesis Gravidarum
- Ondansetron
- Serotonin Antagonists